Figure 3
Intracellular adhesion molecule (ICAM) mRNA expression in the injured cortex measured using quantitative real-time PCR. (A) ICAM mRNA at 6 hours, 2 and 3 days after CCI injury compared to control, *P < 0.05. (B) ICAM mRNA at 1 day after CCI injury in wild-type mice treated with a cannabinoid type-2 (CB2) agonist (0-1966) and CB2 antagonist (SR144528) compared to vehicle-treated CCI controls, **P < 0.01. (C) ICAM mRNA at 1 day after CCI injury in CB2 knockout (CB2 -/-) mice and wild-type mice compared to control, **P < 0.01 and ***P < 0.001; ICAM mRNA post-CCI in CB2 knockout (CB2 -/-) mice compared to wild-type mice, #P < 0.05.