Figure 5From: Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis S1P, recombinant human plasma gelsolin (rhGSN) and FTY720P prevent release of IL-6 from rat astrocytes. IL-6 release from rat astrocytes 8 hours after addition of S1P, (rhGSN and FTY720P (A). Decrease of IL-6 release from rat astrocytes activated with S1P (5 μM) in the presence of rhGSN (5 μM) and FTY720P (5 μM) (B). *Significantly different. Error bars represent standard deviation of the mean. IL-6 - interleukin 6, S1P - shingosine-1-phosphateBack to article page