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Table 1 Baseline demographic and laboratory features of subjects and follow-up duration

From: Progressive increase in central nervous system immune activation in untreated primary HIV-1 infection

Baseline feature/lab value Median (interquartile range)
Total number of subjects 81
Male (%) 77 (95.1)
Age (years) 36 (28 to 45)
Duration since transmission at baseline (days) 100 (54 to 153)
Blood CD4+ T-cells (cells/μL) 552 (389 to 720)
Plasma HIV RNA (log10 copies/mL) 4.56 (3.97 to 5.18)
CSF HIV RNA (log10 copies/mL) 2.77 (1.80 to 3.47)
Plasma neopterin (nmol/L) 15.1 (9.4 to 21.6)
CSF neopterin (nmol/L) 10.2 (6.6 to 21.3)
% Blood CD4 + CD38 + HLA-DR + a 7.5 (6.2 to 11.6)
% Blood CD8 + CD38 + HLA-DR + a 55.3 (47.4 to 68.1)
% CSF CD4 + CD38 + HLA-DR + a 14.2 (8.5 to 22.2)
% CSF CD8 + CD38 + HLA-DR + a 70.9 (60.9 to 80.6)
Total number of visits 2 (1 to 3)
Duration of follow-up (days) 321 (105 to 727)
  1. an = 42 for flow cytometry analysis. CD, cluster of differentiation; CSF, cerebrospinal fluid; HLA-DR, human leukocyte antigen-D-related.