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Table 1 Baseline demographic and laboratory features of subjects and follow-up duration

From: Progressive increase in central nervous system immune activation in untreated primary HIV-1 infection

Baseline feature/lab value

Median (interquartile range)

Total number of subjects

81

Male (%)

77 (95.1)

Age (years)

36 (28 to 45)

Duration since transmission at baseline (days)

100 (54 to 153)

Blood CD4+ T-cells (cells/μL)

552 (389 to 720)

Plasma HIV RNA (log10 copies/mL)

4.56 (3.97 to 5.18)

CSF HIV RNA (log10 copies/mL)

2.77 (1.80 to 3.47)

Plasma neopterin (nmol/L)

15.1 (9.4 to 21.6)

CSF neopterin (nmol/L)

10.2 (6.6 to 21.3)

% Blood CD4 + CD38 + HLA-DR + a

7.5 (6.2 to 11.6)

% Blood CD8 + CD38 + HLA-DR + a

55.3 (47.4 to 68.1)

% CSF CD4 + CD38 + HLA-DR + a

14.2 (8.5 to 22.2)

% CSF CD8 + CD38 + HLA-DR + a

70.9 (60.9 to 80.6)

Total number of visits

2 (1 to 3)

Duration of follow-up (days)

321 (105 to 727)

  1. an = 42 for flow cytometry analysis. CD, cluster of differentiation; CSF, cerebrospinal fluid; HLA-DR, human leukocyte antigen-D-related.