Vitamin D deficiency decreases survival of bacterial meningoencephalitis in mice

Table 1 Subpopulations of T cells in animals fed a diet containing different amounts of vitamin D 20 hours after infection

	Percentage of all CD45 ⁺ cells ^a
	S-VitD	L-VitD	H-VitD
T cells (CD45⁺CD3⁺)	11.25 (4/23.53)	7.5 (1.1/18.50)	10.70 (2.75/23.35)
Regulatory T cells (CD45⁺CD4⁺CD3⁺CD25⁺FoxP3⁺)	0.25 (0.04/0.93)	0.05 (0.005/0.17)	0.09 (0.015/0.5)
NK cells (CD45⁺NK1.1CD3⁻)	2.25 (1.525/3.43)	3 (0.95/4.4)	1.3 (1.15/1.65)
Inflammatory monocytes (CD45⁺CD11b⁺Ly6C^highCCR2⁺)	28.90 (26.95/34.75)	36.20 (25.9/40.85)	27 (18.10/31.20)
Monocytes (CD45⁺CD11b⁺Ly6C^intCCR2⁻)	35.35 (33.3/43.33)	42.20 (31.4/47.3)	34.40 (25.75/37.85)
Granulocytes (CD45⁺CD11b⁺Ly6G⁺CCR2⁻)	43.25 (28.85/51.58)	26.20 (23/49.95)	34.20 (28.60/54.40)

^aData are medians (25th/75th percentiles) determined by forward and side-scatter properties from the whole brain of animals (four or five mice per group) of at least three separate experiments. Significant differences were not found (P > 0.05; one-way ANOVA followed by Bonferroni correction for multiple comparisons). L-VitD low vitamin D supplementation; S-VitD, standard vitamin D supplementation; H-VitD, high vitamin D supplementation.

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