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Figure 7 | Journal of Neuroinflammation

Figure 7

From: Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson’s disease models are mediated by GPR109A-dependent mechanisms

Figure 7

β-hydroxybutyric acid (BHBA) inhibits lipopolysaccharide (LPS)-Induced production of pro-inflammatory enzymes via GPR109A in primary rat microglial cells. Attenuation by BHBA (1.5 mM) of LPS-induced production of iNOS (A, B) and COX-2 (A, C) from primary rat microglial cells in vitro, this effect is abolished with silencing of GPR109A (**P <0.01).

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Journal of Neuroinflammation

ISSN: 1742-2094