Figure 2

A-D Temporal profile of LBP, IL-10, IL-6 and CRP in patients with and without infection. Comparison of time courses between patients with (n = 16) and patients without (n = 16) infection matched for S100B peak levels for the extent of brain damage. Data are presented as median with interquartile range. Intergroup comparisons between patients with and without infection: *P ≤0.05; **P ≤0.01; ***P ≤0.001. Within-group comparisons of marker levels between initial (6 h) and follow-up time points: Patients with infection: significant differences were detected for LBP (6 h versus 12 h: P = 0.001, 6 h versus 24 h: P = 0.001, 6 h versus 3 d: P = 0.01) and CRP (6 h versus 12 h: P = 0.002, 6 h versus 24 h: P = 0.001, 6 h versus 3 d: P = 0.002). Patients without infection: significant differences were detected for LBP (6 h versus 24 h: P = 0.005, 6 h versus 3 d: P = 0.005, 6 h versus 7 d: P = 0.007) and CRP (6 h versus 24 h: P = 0.001).