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Table 4 Fold change values for RT-PCR in APP/PS1 transgenic mice

From: Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice

Gene GFP-AAV IL-4-AAV
IL1β 1.20 ± 0.27 4.63 ± 0.67
INFγ 1.20 ± 0.39 1.70 ± 0.32
IL6 1.33 ± 0.40 2.43 ± 0.38
IL12a 1.18 ± 0.31 3.60 ± 1.64
TNFα 0.74 ± 0.51 1.24 ± 0.15
IL1ra 1.41 ± 0.44 16.24 ± 3.62
YM1 1.90 ± 1.04 979.43 ± 251.30
ARG1 1.27 ± 0.40 216.17 ± 65.91
FIZZ1 2.80 ± 1.74 767.81 ± 108.26
CD86 1.19 ± 0.29 1.91 ± 0.36
FCγR1 1.22 ± 0.33 1.23 ± 0.07
FCγR3 1.15 ± 0.26 1.61 ± 0.17
TGFβ1 1.21 ± 0.30 1.62 ± 0.28
SPHK1 1.03 ± 0.10 1.61 ± 0.12
  1. Bold font indicates P < 0.05 compared to GFP-AAV of that time point and genotype.