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Figure 1 | Journal of Neuroinflammation

Figure 1

From: RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cells

Figure 1

Induction of inflammatory response-related genes in LPS-stimulated BV-2 microglial cells. Quantitative real-time reverse transcriptase PCR analysis of the expression of inflammatory genes in BV-2 microglial cells stimulated with LPS (10 ng/mL). Inflammatory genes were significantly upregulated in cells treated with LPS compared to untreated cells (*P < 0.05 and **P < 0.001) at the indicated times. Gene expression was normalized to GAPDH transcript levels. The data represent three independent experiments. The values are the mean ± SD of triplicate wells. LPS, lipopolysaccharide; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; Tnf-α, tumor necrosis factor alpha.

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Journal of Neuroinflammation

ISSN: 1742-2094