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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Role for cFMS in maintaining alternative macrophage polarization in SIV infection: implications for HIV neuropathogenesis

Figure 3

Accumulating perivascular and nodular CD163 + MΦs/microglia are a major source of M-CSF in SIVE. Parenchymal CD163+ microglia (A) do not appear to express M-CSF in white matter (C); however, M-CSF is produced by other glia (B). Significant co-localization of CD163 (D, G) and M-CSF (E, H) is seen within perivascular cuffs and nodular lesions (F, I) and appears to be the principal source of M-CSF in SIVE brain.

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Journal of Neuroinflammation

ISSN: 1742-2094