Figure 1

The combination of prolactin (PRL) and IFN-β attenuated EAE clinical severity, relative to vehicle and either treatment alone. (A) Mean clinical EAE scores from Tx days 9 to 17 with sacrifice at day 21 (bars indicate SEM). (B) Sum of EAE scores from Tx days 9 to 17 with sacrifice at day 21, with each circle, square, or triangle depicting a separate animal: **P < 0.01; *P < 0.05. There were seven vehicle mice, six PRL-alone animals, and four each of IFN-β alone or the combination group.