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Table 1 Genes induced 2-fold by DFP and suppressed 50% or more by NRG-1

From: Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent-induced delayed neuronal injury

Transcript cluster ID Gene symbol Description FC OP vs. control FC OP/NRG-1 vs. OP
1367794_at A2m Alpha-2-macrolobulin 2.34 −2
1369625_at Aqp1 Aquaporin 1 5.1 −17.93
1383946_at Cldn 1 Claudin 1 3.94 −5.7
1375933_at Cldn 2 Claudin 2 2.44 −25.97
1393891_at Col8a 1 Collagen, type VIII, alpha 1 2.73 −5.42
1374172_at Col8a 2 Collagen, type VIII, alpha 2 3.37 −19.49
1370391_at Crabp 2 Cellular retinoic acid binding protien 2 2.18 −2.04
1379365_at Cxcl 11 Chemokine (C-X-C motif) ligand 11 17.41 −2.13
1368760_at Cxcl 2 Chemokine (C-X-C motif) ligand 2 2.67 −2.61
1367700_at Fmod Fibromudolin 2.02 −8.91
1387889_at Folr 1 Folate receptor 1 (adult) 3.9 −12.25
1368337_at Glycam Glycosylation-dependent cell adhesion molecule 1 3.81 −7.01
1393840_at Gnat 2 Guanine nucleotide protein (G protein), alpha transducing activity polypeptide 2 2.68 −2.52
1391915_at Hspa 9 Heat shock protein 9 2.02 −2.13
1398256_at II 1b Interleukin 1 beta 3.08 −2.13
1387050_s_at Kng 1 Kininogen 1; kininogen 1-like 1; kininogen 2 3.46 −3.31
1387868_at Lbp Lipopolysaccharide binding protien 3.31 −2.62
1387164_at Lect 1 Leukocyte cell derived chemotaxin 1 4.8 −5.56
1393210_at LOC100361383 Extracellular matrix protein 2-like 2.11 −2.09
1375465_at Otx 2 Homeobox protein OTX2-like; orthodenticle homeobox 2 2.51 −17.47
1375908_at Mpzl 2 Myelin protein zero-like 2 4.06 −4.16
1368302_at Msx1 Msh homeobox 1 2.04 −5.63
1371849_at Nt5dc2 5′-nucleotidase domain 2 2.13 −4.9
1385248_a_at Ogn Osteoglycin 2.38 −2.16
1375367_at Pdlim PDZ and LIM domain 2 2.67 −3.73
1370068_at Pla2g5 Phospholipase A2, group V 3.01 −7.5
1371050_at Pon1 Paraoxonase 1 2.48 −3.99
1370012_at Ptgis Prosta landin l2 (prostacyclin) synthase 2.75 −2.74
1380334_at Rbm47 RNA binding motif protein 47 2.11 −3.46
1385500_at RGD1561795 Similar to RIKEN cDNA 1700012B09 2.96 −5.52
1387125_at S100a9 S100 calcium binding protein A9 6.6 −2.88
1377034_at Serpin1a Serine (or cysteine) proteinase inhibitor, clade B, member 1a 3.07 −2.2
1385005_at Slc22a8 Solute carrier family 22 (organic anion transporter), member 8 2.12 −3.45
1368606_at Slco1a5 Solute carrier organic transporter family, member 1a5 4.34 −48.37
1367998_at Slpi Secretory leukocyte peptidaase inhibitor 5.12 −2.32
1390525_a_at Stra6 Stimulated by retinoic acid gene 6 2.64 −4.31
1384522_at Sytl3 Synaptotagmin-like 3 2 −2.06
1383606_at Tc2n Tandem C2 domains, nuclear 4.01 −3.59
1387013_at Tmem27 Transmembrane protein 27 4.53 −34.51
1388557_at Tubb4b Tubulin, beta 4B class IVb 2.24 −4.21
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Journal of Neuroinflammation

ISSN: 1742-2094