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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli

Figure 2

Age is associated with increased macrophage infiltration and chemokine expression. There was a significant increase in the percentage of macrophages (A) in the brains of older rats (* P < 0.05; Student’s t-test; n = 4); values are presented as means (±SEM). (B) A representative plot of the flow cytometry data. There was an age-related increase in IP-10 (C) and MCP-1 (D) mRNA expression in hippocampal tissue (* P < 0.05; Student’s t-test; n = 6 to 15). For mRNA data, values are presented as means (±SEM) and expressed as a ratio to β-actin mRNA. IP-10, interferon gamma-induced protein 10; MCP-1, monocytes chemotactic protein 1; RQ, relative quantities.

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