Early lipopolysaccharide (LPS) administration causes transient body and brain weight loss and decreases the cerebellar area. (A) Body and brain of CD1 wild-type mice were weighed at 1 and 9 days post-LPS administration. (B) Body weight of C57BL/6 (B6) CX3CR1gfp/+ mice was assessed at days 1/3/5/7/9 after LPS injection. (C) Cerebellar area was measured in tiled confocal images of brain sections from B6 CX3CR1gfp/+ mice at days 1/3/5/7/9 post-LPS (representative images with DAPI in (D). Results are mean ± SEM from at least four animals. **P < 0.01 vs. without (W/O) LPS.