Figure 5

Effect of ATK on CEC-induced increased levels of PGE2 and LTB4. The levels of PGE2 (A, B) and LTB4 (C, D) were measured using ELISA at 24 h after CEC in the spinal cord tissue from epicenter region (E) and serum. The levels of both PGE2 and LTB4 were significantly increased in CEC + VEH group in the spinal cord (A, C) as well as in the serum (B, D). ATK treatment decreased the levels of both. Data are expressed as mean ± SD (n = 5). Results are presented as pg/mg protein for spinal cord tissue and pg/ml in serum. **p < 0.01, ***p < 0.001 vs. Sham and CEC + ATK, ###p < 0.001 vs. Sham.