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Table 3 Clinical results from hAEC dose titration

From: Immunosuppressive potential of human amnion epithelial cells in the treatment of experimental autoimmune encephalomyelitis

 

hAEC 0.1

hAEC 0.25

hAEC 0.5

PBS

Disease incidence

5/6

5/6

5/6

7/7

Day disease onset

12.8 ± 0.6

17.0 ± 3.7

14.0 ± 1.3

12.0 ± 0.4

Death severe disease

1/6

2/6

0/6

2/7

Maximum score

2.3 ± 0.7

3.1 ± 0.8

1.8 ± 0.5*

3.6 ± 0.4

Cumulative score

37.6 ± 11.3

24.3 ± 7.8**

17.8 ± 7.5**

71.2 ± 11.1

  1. *P < 0.05, **P < 0.01, compared to PBS
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Journal of Neuroinflammation

ISSN: 1742-2094