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Table 3 Clinical results from hAEC dose titration

From: Immunosuppressive potential of human amnion epithelial cells in the treatment of experimental autoimmune encephalomyelitis

  hAEC 0.1 hAEC 0.25 hAEC 0.5 PBS
Disease incidence 5/6 5/6 5/6 7/7
Day disease onset 12.8 ± 0.6 17.0 ± 3.7 14.0 ± 1.3 12.0 ± 0.4
Death severe disease 1/6 2/6 0/6 2/7
Maximum score 2.3 ± 0.7 3.1 ± 0.8 1.8 ± 0.5* 3.6 ± 0.4
Cumulative score 37.6 ± 11.3 24.3 ± 7.8** 17.8 ± 7.5** 71.2 ± 11.1
  1. *P < 0.05, **P < 0.01, compared to PBS