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Table 1 Study subjects for the assessment of IL-22 and IL-22BP in the blood

From: Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes

Category

N = 141

Male/female ratio

Age at blood draw (years)a

EDSSa

Disease duration (years)a

Last relapse (months)a

Clinically active MS patients

26

7/19

31.5 ± 10.0

2.00 ± 1.00

0.63 ± 7.19

0.46 ± 0.82

Clinically inactive MS patients

35

10/25

39.5 ± 11.5

1.50 ± 0.63

7.00 ± 9.25

16.87 ± 34.43

Progressive MS patients

35

12/23

52.0 ± 15.0

4.50 ± 2.50

17.0 ± 12.0

–

Healthy control subjects

45

21/24

34.0 ± 28.5

–

–

–

  1. MS multiple sclerosis, EDSS expanded disability status scale
  2. aMedian ± interquartile range