Fig. 6
Neuroprotective and lipid peroxidation effects of SB332235 on GCL neurons. a Representative neuronal staining (NeuN) in PBS control (upper left panel), SB332235 alone (upper right panel), Aβ1–42 (lower left panel), and Aβ1–42 + SB332235 (lower right panel); results are for 3 days post-injection; scale bar represents 50 μm. b Area density of NeuN for the animal groups, N = 5 per group. Asterisk denotes p < 0.05. c Typical lipid peroxidation (4-HNE marker) levels following 3 days intrahippocampal injection of PBS (upper left panel), SB332235 alone (upper right panel), Aβ1–42 (lower left panel), and Aβ1–42 + SB332235 (lower right panel). Scale bar is for 50 μm. d Area density of 4-HNE for the different animal treatments, N = 5 per group. *p < 0.05 for Aβ1–42 vs PBS and #p < 0.05 for Aβ1–42 vs Aβ1–42 + SB332235