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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Chronic morphine and HIV-1 Tat promote differential central nervous system trafficking of CD3+ and Ly6C+ immune cells in a murine Streptococcus pneumoniae infection model

Fig. 6

Ly6C+ cells transport S. pneumoniae across the blood-brain barrier. Confocal microscope and z-stacked images of mouse prefrontal region brain cryostat sections (5 μm) showing co-localization of immune cells, CD3+ and Ly6C+ cells (Alexa Fluor 488-conjugated anti-mouse IgG; green), with S. pneumoniae. Merged images show co-localization of S. pneumoniae (Rhodamine Red goat anti-rabbit IgG; red) with Ly6C+ cells. Nuclei were counterstained with DAPI (blue). Magnification ×2400. Scale bar 10 μm

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Journal of Neuroinflammation

ISSN: 1742-2094