Fig. 2

DRα1-mMOG-35-55 treats clinical EAE. C57BL/6 male WT mice with mMOG-35-55-induced EAE were treated after disease onset at a clinical score of 2 with vehicle or DRα1-mMOG-35-55 (100 μg daily × 5, black arrows). Mean clinical EAE daily disease scores (left) and cumulative disease index scores (right) are shown. **p < 0.01, ***p < 0.001. Daily mean scores were analyzed by Mann–Whitney U and mean CDI by Student’s t test