Fig. 6

Time course of ICAM-1 and VCAM expression following IL-1β and TNFα activation reveals a time- and cytokine-dependent profile of expression. Cell-surface expression of (a) CD54 (ICAM-1) and (b) CD106 (VCAM-1) over a 6-day period under basal condition, following endothelial activation with IL-1β (5 ng/mL) or TNFα (5 ng/mL). Expression levels are represented as MFI (mean fluorescent intensity). The right-hand panels show the individual flow plots to highlight the bimodal expression profile present for VCAM-1. Data are representative of three independent experiments