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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Increased CCL2, CCL3, CCL5, and IL-1β cytokine concentration in piriform cortex, hippocampus, and neocortex after pilocarpine-induced seizures

Fig. 4

A significant increase in IL-1β concentration was observed in the piriform cortex, hippocampus, and neocortex 2 h after SE (*p < 0.05) and in the hippocampus and neocortex 6 h after SE (*p < 0.05), but not in the cerebellum. The peak concentration was observed 24 h after SE with a ~2-fold increase in the piriform cortex (*p < 0.05) and a ~2.5-fold in the neocortex (*p < 0.001) with no significant alteration in the hippocampus. Five days after seizures, IL-1β levels returned to control levels in all brain regions

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Journal of Neuroinflammation

ISSN: 1742-2094