Table 1 Average cytokine concentration in pg/μg of total protein
Analytes | Brain region | 2 h | 6 h | 24 h | 5 days | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Cytokines | Chemokines | Control | SE | Control | SE | Control | SE | Control | SE | |
CCL2 | Piriform | 3.6 | 10.7 | 3.7 | 34.8 | 3.7 | 694.8 | 3.6 | 22.8 | |
Hippocampus | 3.7 | 16.3 | 4.4 | 81.6 | 2.2 | 243.8 | 4.4 | 26.8 | ||
Neocortex | 2.9 | 21.7 | 3.5 | 97.0 | 3.7 | 933.3 | 3.8 | 15.5 | ||
Cerebellum | 1.4 | 1.8 | 1.4 | 1.9 | 2.8 | 4.0 | 3.8 | 5.7 | ||
CCL3 | Piriform | 0.4 | 24.3 | 1.7 | 29.8 | 0.2 | 50.3 | 0.3 | 15.6 | |
Hippocampus | 0.5 | 31.4 | 1.2 | 30.6 | 0.2 | 42.2 | 0.1 | 29.3 | ||
Neocortex | 0.9 | 32.3 | 0.9 | 23.3 | 0.1 | 37.7 | 0.3 | 22.1 | ||
Cerebellum | 0.2 | 0.2 | 0.0 | 0.0 | 0.0 | 0.9 | 0.0 | 0.0 | ||
CCL5 | Piriform | 6.7 | 8.2 | 8.1 | 10.3 | 6.0 | 13.8 | 6.6 | 10.1 | |
Hippocampus | 4.9 | 5.8 | 5.8 | 5.9 | 6.6 | 10.6 | 4.5 | 6.7 | ||
Neocortex | 8.6 | 8.9 | 7.9 | 10.5 | 8.2 | 14.2 | 8.4 | 8.2 | ||
Cerebellum | 7.1 | 5.9 | 7.1 | 6.2 | 7.2 | 6.0 | 6.8 | 5.8 | ||
IL-1β | Piriform | 5.0 | 7.7 | 5.2 | 7.8 | 6.2 | 12.2 | 6.1 | 6.7 | |
Hippocampus | 5.5 | 8.5 | 6.0 | 8.5 | 5.9 | 7.7 | 5.8 | 6.4 | ||
Neocortex | 6.4 | 10.0 | 5.6 | 9.1 | 5.7 | 13.4 | 6.4 | 8.0 | ||
Cerebellum | 6.0 | 6.4 | 5.0 | 5.7 | 5.3 | 6.5 | 5.7 | 6.7 | ||
TNF | Piriform | 1.3 | 1.0 | 0.7 | 0.8 | 1.2 | 0.6 | 1.1 | 1.6 | |
Hippocampus | 1.6 | 1.6 | 1.3 | 1.9 | 2.5 | 1.6 | 1.5 | 2.8 | ||
Neocortex | 1.2 | 1.5 | 1.0 | 1.5 | 0.7 | 1.5 | 2.0 | 1.5 | ||
Cerebellum | 1.0 | 1.0 | 0.5 | 0.4 | 0.6 | 0.5 | 0.6 | 0.9 | ||
(Signal protein) | ||||||||||
VEGF | Piriform | 0.9 | 0.7 | 0.9 | 0.5 | 0.9 | 1.1 | 0.9 | 0.6 | |
Hippocampus | 0.8 | 0.7 | 0.6 | 0.5 | 0.9 | 0.9 | 0.7 | 0.7 | ||
Neocortex | 0.7 | 0.5 | 0.7 | 0.6 | 0.6 | 0.7 | 0.9 | 0.9 | ||
Cerebellum | 0.3 | 0.7 | 0.5 | 0.7 | 0.5 | 0.5 | 0.6 | 0.7 | ||