Fig. 4

Genes with discriminatory power in cluster analysis. Gene expression values for MHC class II, CD4, CD68, OAS-1, COX-2, NAMPT, and IL-1β in CSF cell samples from RRMS patients clustering into groups 1, 2, and 3 are shown. Significant differences in gene expression between group 1 (n = 24) and group 2 (n = 6) patients were assessed by Mann-Whitney test; p values ≤0.0125 are shown. Each dot represents the gene expression value obtained in each individual patient; the line marks the median value