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Table 2 The effect of a high-fat diet on haematological parameters

From: Prolonged diet-induced obesity in mice modifies the inflammatory response and leads to worse outcome after stroke

 

Control

High-fat diet

Total WBC (× 103/μl)

19.3 ± 0.9

27.6 ± 3.4*

Neutrophils (×103/μl)

1.84 ± 0.09

3.59 ± 0.8**

Lymphocytes (× 103/μl)

17.2 ± 0.9

23.7 ± 2.6*

Monocytes (× 103/μl)

0.01 ± 0.004

0.04 ± 0.01

Eosinophils (× 103/μl)

0.08 ± 0.02

0.06 ± 0.02

Basophils (× 103/μl)

0.13 ± 0.03

0.15 ± 0.04

LIC (× 103/μl)

0.05 ± 0.01

0.07 ± 0.01

RBC (× 106/μl)

8.3 ± 0.4

11.5 ± 0.7***

HGB (g/dl)

12.0 ± 0.5

17.2 ± 0.9***

HCT (%)

39.8 ± 1.7

57.3 ± 3.3***

MCV (fL)

48.3 ± 0.8

49.6 ± 0.4**

RDW (%)

12.1 ± 0.3

12.8 ± 0.2*

Platelets (× 103/μl)

1200 ± 114

1353 ± 85

MPV (fL)

5.4 ± 0.1

5.3 ± 0.05

PCT (%)

0.11 ± 0.01

0.12 ± 0.01

  1. Mice were maintained on a high-fat or control diet for 6 months. Blood obtained from the tail vein was analysed using a Pentra ES 60 haematometer
  2. HCT haematocrit HGB haemoglobin, LIC large immature cells, MCV mean corpuscular volume, MPV mean platelet volume, PCT plateletcrit, RBC red blood cells, RDW red cell distribution width, WBC white blood cells
  3. Data are mean ± standard error of the mean (SEM), n = 10–12/group
  4. *P < 0.05, **P < 0.01, ***P < 0.001 versus control-fed mice. Student’s t-test
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Journal of Neuroinflammation

ISSN: 1742-2094