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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Chronic inflammatory demyelinating polyneuropathy (CIDP): change of serum IgG dimer levels during treatment with intravenous immunoglobulins

Fig. 3

Monomerized dimeric IgG fractions of CIDP patients stained axonal and myelin structures of the peripheral nerve. a Double immunofluorescence labeling with Hoechst counterstain (cell nuclei, blue) revealed binding of monomerized dimeric IgG fractions (red) from CIDP patients to myelin basic protein (green). b Control IgG showed no specific binding. Also, double immunofluorescence labeling with Hoechst counterstain (cell nuclei, blue) showed binding of monomerized dimeric IgG from CIDP patients (red) to axonal nerve structures (beta-III tubulin, green) (c), whereas no binding was observed in control staining (d) (scale bar 50 μm)

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Journal of Neuroinflammation

ISSN: 1742-2094