Fig. 2

CSF1R inhibition does not alter cognition or behavior in adult mice. a Two-month-old wild-type mice were treated with either vehicle, 300 or 1200 mg/kg PLX5622 for 14 days, and behavioral analyses were conducted using an open-field test and Barnes maze. b–e No differences were measured across groups in the open-field test in distance traveled, velocity, time spent in open arena, or time spent in edge of arena. f–g No differences were measured across groups in the Barnes maze in acquisition of time to find escape hole or in probe trial. Error bars indicate SEM