Fig. 1
C5b-9 is expressed in brain during experimental pneumococcal meningitis. C5b-9 (μg/mg) protein levels in brain of WT mice inoculated with sterile saline (n = 6) or 107 CFU/ml of S. pneumoniae serotype 3 (n = 24) and sacrificed at 6 or 24 h post inoculation. Mice with pneumococcal meningitis showed increased brain C5b-9 levels compared to saline-inoculated mice at 24 h after inoculation (median 0.78 vs. 2.53 μg/mg tissue, Mann-Whitney U test P = .001). Lines represent median values