Fig. 2

Disaggregation of preformed Aβ fibrils by an N-terminal antibody increases the neurotoxicity of Aβ in vitro. a Representative images of annexin V staining in SH-SY5Y cells treated with the co-incubates of antibodies and Aβ. The neurons were counterstained with DAPI. Scale bar = 100 μm. b Quantification of the percentages of annexin V-labelled neurons. c MTT assays showing the cell viability of SH-SY5Y cells. d Representative images of SH-SY5Y cells treated with co-incubates of antibodies and Aβ. e Quantification of the neurite length of SH-SY5Y cells. **P < 0.01 vs control, ##P < 0.01 vs PBS