Fig. 6

An RIP2 inhibitor reduces Jo2-induced HMGB1 release by Wt retinal cells. Retinal explants from Wt mice were cultured for 6 h with medium or medium containing 1 μg/ml of Jo2 in the presence or absence of an RIP2 inhibitor (SB) (1 μg/ml), then HMGB1 levels in the culture supernatants were measured by ELISA. **p < 0.01 compared to retinal explants treated with medium by one-way ANOVA