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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Induction of virus-specific effector immune cell response limits virus replication and severe disease in mice infected with non-lethal West Nile virus Eg101 strain

Fig. 6

Leukocyte accumulation in the spleens of WNV NY99 and WNV Eg101 infected mice. Spleens were harvested from mock, WNV NY99, and WNV Eg101 infected mice after extensive perfusion at day 8 after inoculation. Splenocytes were isolated and analyzed by flow cytometry. a Total number of leukocytes (CD45+), T cells (CD45+ CD3+), CD4+ T cells (CD45+ CD3+ CD4+), CD8+ T cells (CD45+ CD3+ CD8+), NK cells (CD45+ CD3− NK1.1+), and monocytes/macrophages (CD45+ CD11b+ Ly6c+) per spleen. Data represents the mean ± SEM, representing two independent experiments (n = 6 mice per group). *p < 0.05. b Representative flow cytometry profiles demonstrating percentages of NK cells, and monocytes/macrophages in the spleen at day 8 after inoculation. Data represents two independent experiments (n = 6 mice per group)

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Journal of Neuroinflammation

ISSN: 1742-2094