Fig. 5

The levels of PV, 4-HNE, and gp91^phox in the PFC and hippocampus. a, b Sepsis induced significant decreases in the PV level from day 3 to day 14 and significant increases in the 4-HNE level from 24 h to day 3 in the hippocampus. c–f The PV level was decreased and the gp91^phox level was increased in the hippocampus at day 14 but not at day 30 in the CLP + vehicle group compared with the sham groups, whereas apocynin treatment reversed these abnormities. There was no significant difference in the PV and gp91^phox levels in the PFC among the four groups. Data are presented as mean ± SEM (n = 6). ^# p < 0.05 vs the sham groups; *p < 0.05 vs the CLP + vehicle group