Table 2 Change in CES-D score and serum amino acids
From: Targeting inflammation to influence mood following spinal cord injury: a randomized clinical trial
Treatment (n = 12) | Control (n = 8) | |||||
|---|---|---|---|---|---|---|
Baseline | 1 month | 3 months | Baseline | 1 month | 3 months | |
CES-D score*** | 14.5 ± 10.7 | 6.8 ± 5.6** | 6.5 ± 5.0** | 13.9 ± 12.0 | 11.3 ± 10.3* | 14.6 ± 13.6 |
TRP (μmol/L) | 89.2 ± 19.4 | 87.6 ± 28.8 | 90.7 ± 26.7 | 107.8 ± 28.1 | 105.9 ± 20.3 | 102.6 ± 14.4 |
Tyrosine (μmol/L) | 48.2 ± 17.7 | 50.5 ± 15.1 | 41.5 ± 15.2 | 59.4 ± 17.6 | 53.7 ± 15.7 | 62.2 ± 18.3 |
Phenylalanine (μmol/L) | 36.6 ± 13.6 | 36.8 ± 13.6 | 33.6 ± 14.8 | 42.0 ± 16.6 | 40.8 ± 18.2 | 46.2 ± 23.4 |
BCAA (μmol/L) | 700.2 ± 462.4 | 651.3 ± 351.9 | 467.9 ± 198.5 | 449.7 ± 105.5 | 472.2 ± 112.1 | 534.3 ± 159.2 |
LNAA (μmol/L) | 785.0 ± 468.2 | 738.6 ± 352.3 | 543.1 ± 217.3 | 551.2 ± 108.7 | 566.8 ± 123.8 | 642.7 ± 190.3 |
TRP/LNAA*** | 146.9 ± 71.3 | 133.6 ± 52.3 | 188.7 ± 90.4 | 206.3 ± 79.6 | 194.0 ± 51.2 | 171.2 ± 49.8 |
KYN (μmol/L) | 2.3 ± 0.7 | 2.3 ± 0.6 | 2.1 ± 0.4 | 1.7 ± 0.4 | 2.1 ± 0.3 | 2.1 ± 0.4 |
PHE/TYR | 786.8 ± 232.2 | 738.1 ± 229.5 | 809.5 ± 180.4 | 746.6 ± 247.1 | 751.08 ± 219.1 | 732.78 ± 267.2 |
KYN/TRP | 27.0 ± 11.6 | 28.5 ± 10.9 | 24.0 ± 6.6 | 16.8 ± 4.9 | 20.3 ± 4.7 | 20.6 ± 6.0 |