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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit

Fig. 4

Effects of LPS and indomethacin on microglial/macrophage and astrocytic activation. Microglial/macrophage activation was increased by LPS but not blocked by indomethacin as assessed by Iba1 (left-hand panels) and by F4/80 (middle panels) immunohistochemistry. Astrocytic activation was increased by LPS and blocked by indomethacin as assessed by GFAP staining (right-hand panels). The bottom three panels show quantification of Iba1 (n = 5–6/statistical cell), F4/80 (n = 5–6), and GFAP (n = 4–5) immunohistochemical staining. *p < 0.05, **p < 0.01, ***p < 0.001, Mag = ×20

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Journal of Neuroinflammation

ISSN: 1742-2094