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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system

Fig. 1

CCR5 is necessary to reduce WNV-associated disease and mortality. WT and CCR5−/− mice were infected with 102 PFU of WNV via the subcutaneous route. a Survival was monitored for 28 days after infection. n = 30 mice, *P = 0.0503 (log-rank test). b Clinical scores were monitored daily for 12 days after infection. The designation for the clinical scores is as follows: 1 ruffled fur/hunched; 2 altered gait, slow movement; 3 not moving but responsive; 4 moribund; and 5 death. c Individual clinical scores are shown at each time point for WT (left) and CCR5/ (right) mice. Asterisks indicate values that are statistically significant (**P < 0.005, ***P < 0.001)

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