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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Antagonist of the neurokinin-1 receptor curbs neuroinflammation in ex vivo and in vitro models of Lyme neuroborreliosis

Fig. 5

Apoptosis in DRG cell cultures. a Non-apoptotic field of neurons (NeuN-positive cells, red) cultured from rhesus DRG as visualized by fluorescent microscopy. b DNA fragmentation detected by the TUNEL assay (green) as visualized by fluorescent microscopy. c Graphical representation of the percent neuronal apoptosis as quantified by the TUNEL assay in cultured DRG cells exposed for 24 h to B. burgdorferi (Bb), exposed to B. burgdorferi, and treated with NK1R antagonist (Bb + A), in medium alone (Med), and medium plus antagonist (Med + A) (**p < 0.001)

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Journal of Neuroinflammation

ISSN: 1742-2094