Fig. 6

Microglia activation. Microglia activation is reflected by the ratio of the coverage of the cell bodies to the total coverage (cell bodies and processes). Data are given as percentages of the sham + PBS group. a Microglia activation in the CA3 area of the hippocampus. b Microglia activation in the CA1 area of the hippocampus. c Microglia activation in the hippocampal dentate gyrus. d Microglia activation in the hippocampal hilus. In all areas, a highly significant main effect for group (LPS/PBS) was found (p < 0.0001 for all areas). The main effects for treatment (sham/ECS) and group × treatment interaction effects did not reach significance for any of the analyzed brain areas