Immune mediator | HSC medium control | HSC + live Bb (10:1) | HSC + live Bb + dexamethasone (150 μM) | HSC + live Bb + meloxicam (100 μM) |
---|---|---|---|---|
IL-1RA | 31.38 ± 0.97 | 84.76 ± 9.75 | 18.10 ± 0.97 | 130.09 ± 29.18 |
p < 0.001 | p < 0.05 | |||
IL-6 | 266.62 ± 12.75 | 1420.76 ± 62.98 | 850.96 ± 19.09 | 1845.76 ± 23.87 |
p < 0.001 | p < 0.001 | |||
IL-8 | 1930.90 ± 129.43 | 10297.62 ± 759.93 | 3093.81 ± 198.68 | 13,686.96 ± 494.18 |
p < 0.001 | p < 0.001 | |||
IL-10 | 34.86 ± 1.45 | 89.11 ± 2.23 | 110.68 ± 2.08 | 92.04 ± 11.43 |
p < 0.001 | ns | |||
IL-12 p70 | 303.45 ± 21.69 | 658.21 ± 29.69 | 367.02 ± 15.02 | 767.67 ± 36.3 |
p < 0.001 | p < 0.05 | |||
IL-15 | 6.56 ± 0.58 | 23.67 ± 2.54 | 11.42 ± 1.34 | 38.49 ± 3.82 |
p < 0.001 | p < 0.001 | |||
CCL2/MCP-1 | 885.83 ± 51.57 | 3227.74 ± 153.35 | 835.10 ± 25.57 | 4719.75 ± 212.96 |
p < 0.001 | p < 0.001 | |||
CCL-5/RANTES | 3.65 ± 0.7 | 38.19 ± 3.79 | 8.49 ± 1.79 | 47.99 ± 3.76 |
p < 0.001 | p < 0.01 | |||
PDGF | 5.65 ± 1.04 | 37.84 ± 4.07 | 14.69 ± 1.74 | 40.38 ± 3.47 |
p < 0.001 | ns | |||
IFN-γ | 34.95 ± 5.48 | 86.33 ± 9.31 | 38.59 ± 3.54 | 112.06 ± 15.18 |
p < 0.001 | ns | |||
IP-10 | 18.94 ± 2.75 | 856.47 ± 73.95 | 365.94 ± 24.53 | 853.49 ± 52.38 |
p < 0.001 | ns | |||
G-CSF | 511.26 ± 56.98 | 3032.42 ± 116.01 | 1725.49 ± 65.32 | 3410.18 ± 97.08 |
p < 0.001 | p < 0.05 | |||
VEGF | 1088.41 ± 162.82 | 5925.06 ± 195.08 | 2920.06 ± 130.67 | 6943.79 ± 172.48 |
p < 0.001 | p < 0.001 | |||
TNF | 5.24 ± 0.9 | 22.22 ± 2.79 | 8.15 ± 1.87 | 24.02 ± 2.69 |
p < 0.001 | ns |