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Table 3 Spearman’s rank correlation coefficients between ISG15, PKR, OAS1, Mx1, and Mx2 protein levels with their gene expression as well as TMEV RNA, inflammation, T cells, B cells, microglia/macrophages, and demyelination in the spinal cord of SJL/J mice

From: Interferon-stimulated genes—essential antiviral effectors implicated in resistance to Theiler’s virus-induced demyelinating disease

ISG protein

ISG mRNA

TMEV RNA

Inflammation (HE)

T cells (CD3)

B cells (CD45R)

Microglia/ Macrophage (MAC3)

Demyelination (LFB)

ISG15

0.499

0.528

0.484

0.445

0.363

0.580

0.316

PKR

0.497

0.417

0.480

0.444

0.371

0.434

0.445

OAS1

0.208

0.118

0.316

0.192

0.163

0.393

0.212

Mx1

0.566

0.566

0.296

0.604

0.675

0.659

0.546

Mx2

0.380

0.537

0.356

0.509

0.465

0.479

0.505

  1. Significant correlations are marked in italics (P ≤ 0.05)