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Table 3 Spearman’s rank correlation coefficients between ISG15, PKR, OAS1, Mx1, and Mx2 protein levels with their gene expression as well as TMEV RNA, inflammation, T cells, B cells, microglia/macrophages, and demyelination in the spinal cord of SJL/J mice

From: Interferon-stimulated genes—essential antiviral effectors implicated in resistance to Theiler’s virus-induced demyelinating disease

ISG protein ISG mRNA TMEV RNA Inflammation (HE) T cells (CD3) B cells (CD45R) Microglia/ Macrophage (MAC3) Demyelination (LFB)
ISG15 0.499 0.528 0.484 0.445 0.363 0.580 0.316
PKR 0.497 0.417 0.480 0.444 0.371 0.434 0.445
OAS1 0.208 0.118 0.316 0.192 0.163 0.393 0.212
Mx1 0.566 0.566 0.296 0.604 0.675 0.659 0.546
Mx2 0.380 0.537 0.356 0.509 0.465 0.479 0.505
  1. Significant correlations are marked in italics (P ≤ 0.05)