Skip to main content
Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Acid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neurons

Fig. 5

Blockage of ASICs inhibits NLRP1 inflammasome activation induced by extracellular acidosis. Representative immunoreactive bands and statistical results showing PcTX1 attenuated acidosis-induced increase in the expression of NLRP1 (a), caspase-1 (b), ASC (c), IL-1β (d), and IL-18 (e). Data are expressed as means ± SEM. n = 6, # p < 0.05 and ##p < 0.01 vs control, *p < 0.05 and **p < 0.01 vs pH 6.5

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094