Table 1 Clinical characteristics of the 29 ASD patients
From: Interleukin-18 modulation in autism spectrum disorders
Patient | Gender | Delivery | Babbling (months) | Age first steps (months) | CARS score | Severity | DSM-IV diagnosis | Comorbidities/other relevant clinical data | Family history | Autoimmune diseases allergy |
|---|---|---|---|---|---|---|---|---|---|---|
1. | M | Natural | 9 | 16 | 36.5 | Moderate | Autistic disorder | Â | Cardiovascular diseases, diabetes, hypertension, dyslipidemia | Dust (mother) |
2. | M | Natural | 12 | 12 | 56 | Severe | Autistic disorder | Impulse dyscontrol disorder | Tumors | Food allergies (mother) |
3. | M | Natural | 7 | 20 | 37 | Moderate | Autistic disorder | Inhalant allergens | Diabetes, hypertension, dyslipidemia, neuropsychiatric diseases | Nickel (mother) |
4. | M | Caesarean section | 6/7 | 18 | 32 | Mild-moderate | Autistic disorder | Specific phobia | Cardiovascular diseases, diabetes, hypertension, dyslipidemia, tumors, neuropsychiatric diseases | Â |
5. | M | Natural | 6 | 12 | 45 | Severe | Autistic disorder | Allergy to Dermatophagoides | Tumors | Psoriasis (mother) |
6. | M | Caesarean section | 6 | 12 | 56.5 | Severe | Autistic disorder | Severe language disorder | Â | Â |
7. | M | Caesarean section | 6 | 12 | 41 | Severe | Autistic disorder | Food allergies | Cardiovascular diseases, obesity, diabetes, hypertension, dyslipidemia, tumors, neuropsychiatric diseases | Pollen (mother) |
8. | M | Natural | 6 | 24 | 41.5 | Severe | Autistic disorder | Â | Cardiovascular diseases, hypertension, tumors | Â |
9. | M | Natural | 6 | Severe hypothonia | 40 | Severe | Autistic disorder | Â | Diabetes, tumors | Psoriasis (mother) |
10. | F | Caesarean section | 7 | 24 | 38 | Severe | Autistic disorder |  | Cardiovascular diseases, obesity, hypertension | Takayasu’s arteritis (mother) |
11. | M | Adopted when he was 2Â years old | Â | Â | 48 | Severe | Autistic disorder | Fish and vegetables allergy | Â | Lactose intolerance (mother) |
12. | M | Natural childbirth | 6Â months | 18Â months | 31 | Mild | D.P.S. NOS | Intolerant to gluten | Hypertension | Lactose intolerance (mother) |
13. | M | Caesarean section | 7/8Â months | 12Â months | 40.5 | Severe | Autistic disorder | Â | Cardiovascular diseases, obesity, Hypertension | Psoriasis (mother) |
14. | M | Natural | 12Â months | 12Â months | 40 | Severe | Autistic disorder | Â | Obesity | Celiac disease (mother) |
15. | M | Natural | 7 | 12 | 33 | Moderate | Asperger disorder | Â | Cardiovascular diseases, obesity, hypertension, tumors | Â |
16. | M | Caesarean section, Premature, Jaundice | 6 | 14 | 30.5 | Mild | Autistic disorder | Previous hydrocephalus | Â | Rheumatoid arthritis (sister), duster (mother) |
17. | M | Natural | 30Â months | 24 | 48 | Severe | Autistic disorder | Discrete obsessive conducted and tendency toward aggression. Cognitive disabilities. Psychopharmacological treatment | Â | Food (mother), drug (father) |
18. | M | Natural | 30Â months | 20 | 38 | Severe | Autistic disorder | Â | Â | Food and Drugs (mother and father) |
19. | M | Caesarean section | 6 | 17 | 20 | Mild | Pervasive disorder NOS | Â | Â | Atopic dermatitis (brother) |
20. | M | Natural | 8/9Â months | 13Â months | 23.5 | Mild | Pervasive disorder NOS | Â | Cardiovascular diseases, obesity, diabetes, hypertension, dyslipidemia | Celiac disease (grand mother), type 1 diabetes (grand mother) |
21. | M | Caesarean section | 30Â months and after regression | 13 | 52 | Severe | Autistic disorder | Â | Cardiovascular diseases, tumors | Rheumatoid arthritis (mother), psoriasis (uncle), ragweed hay fever (aunt) |
22. | M | Natural | 12 followed by regression | 19 | 39.5 | Severe | Autistic disorder | Â | Â | Mite allergy (father), type 1 diabetes (grandfather) |
23. | M | Natural | 6Â months | 13Â months | 24 | Mild | Pervasive disorder NOS | Â | Cardiovascular diseases, hypertension, tumors | No |
24. | M | Caesarean section | 6 | 13 | 25 | Mild | Asperger disorder | Â | Cardiovascular diseases, hypertension, tumors | Oat grass: lactose intolerant (patient), grass allergy (mother, uncle) |
25. | M | Caesarean section | 12Â months | 18Â months | 39 | Severe | Pervasive disorder NOS | Dysgenetic pathology ndd; epileptic syndrome pharmacological treatment | Â | No |
26. | M | Natural | Not reported | 18 | 46 | Severe | Autistic disorder | Epileptic syndrome pharmacological treatment | Â | Psoriasis (father), lactose intolerance (mother) |
27. | M | Caesarean section | 6 | 20 | 51 | Severe | Pervasive disorder NOS | Probable dysgenetic pathology ndd; reduced cognitive skills, ongoing antiepileptic treatment | Cardiovascular diseases, hypertension, dyslipidemia | No |
28. | F | Natural | 6 | 13 | 31 | Mild | Autistic disorder | Â | Cardiovascular diseases, hypertension, tumors | Grass, mite allergies (father) |
29. | M | Natural | 15Â months | 20Â months | 49 | Severe | Autistic disorder | Genetic pathology ndd; moderate-to-severe cognitive disorder | Cardiovascular diseases, hypertension, neuropsychiatric diseases | Nickel allergy (grandmother), psoriasis (mother) |