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Table 1 Clinical characteristics of the 29 ASD patients

From: Interleukin-18 modulation in autism spectrum disorders

Patient Gender Delivery Babbling (months) Age first steps (months) CARS score Severity DSM-IV diagnosis Comorbidities/other relevant clinical data Family history Autoimmune diseases allergy
1. M Natural 9 16 36.5 Moderate Autistic disorder   Cardiovascular diseases, diabetes, hypertension, dyslipidemia Dust (mother)
2. M Natural 12 12 56 Severe Autistic disorder Impulse dyscontrol disorder Tumors Food allergies (mother)
3. M Natural 7 20 37 Moderate Autistic disorder Inhalant allergens Diabetes, hypertension, dyslipidemia, neuropsychiatric diseases Nickel (mother)
4. M Caesarean section 6/7 18 32 Mild-moderate Autistic disorder Specific phobia Cardiovascular diseases, diabetes, hypertension, dyslipidemia, tumors, neuropsychiatric diseases  
5. M Natural 6 12 45 Severe Autistic disorder Allergy to Dermatophagoides Tumors Psoriasis (mother)
6. M Caesarean section 6 12 56.5 Severe Autistic disorder Severe language disorder   
7. M Caesarean section 6 12 41 Severe Autistic disorder Food allergies Cardiovascular diseases, obesity, diabetes, hypertension, dyslipidemia, tumors, neuropsychiatric diseases Pollen (mother)
8. M Natural 6 24 41.5 Severe Autistic disorder   Cardiovascular diseases, hypertension, tumors  
9. M Natural 6 Severe hypothonia 40 Severe Autistic disorder   Diabetes, tumors Psoriasis (mother)
10. F Caesarean section 7 24 38 Severe Autistic disorder   Cardiovascular diseases, obesity, hypertension Takayasu’s arteritis (mother)
11. M Adopted when he was 2 years old    48 Severe Autistic disorder Fish and vegetables allergy   Lactose intolerance (mother)
12. M Natural childbirth 6 months 18 months 31 Mild D.P.S. NOS Intolerant to gluten Hypertension Lactose intolerance (mother)
13. M Caesarean section 7/8 months 12 months 40.5 Severe Autistic disorder   Cardiovascular diseases, obesity, Hypertension Psoriasis (mother)
14. M Natural 12 months 12 months 40 Severe Autistic disorder   Obesity Celiac disease (mother)
15. M Natural 7 12 33 Moderate Asperger disorder   Cardiovascular diseases, obesity, hypertension, tumors  
16. M Caesarean section, Premature, Jaundice 6 14 30.5 Mild Autistic disorder Previous hydrocephalus   Rheumatoid arthritis (sister), duster (mother)
17. M Natural 30 months 24 48 Severe Autistic disorder Discrete obsessive conducted and tendency toward aggression. Cognitive disabilities. Psychopharmacological treatment   Food (mother), drug (father)
18. M Natural 30 months 20 38 Severe Autistic disorder    Food and Drugs (mother and father)
19. M Caesarean section 6 17 20 Mild Pervasive disorder NOS    Atopic dermatitis (brother)
20. M Natural 8/9 months 13 months 23.5 Mild Pervasive disorder NOS   Cardiovascular diseases, obesity, diabetes, hypertension, dyslipidemia Celiac disease (grand mother), type 1 diabetes (grand mother)
21. M Caesarean section 30 months and after regression 13 52 Severe Autistic disorder   Cardiovascular diseases, tumors Rheumatoid arthritis (mother), psoriasis (uncle), ragweed hay fever (aunt)
22. M Natural 12 followed by regression 19 39.5 Severe Autistic disorder    Mite allergy (father), type 1 diabetes (grandfather)
23. M Natural 6 months 13 months 24 Mild Pervasive disorder NOS   Cardiovascular diseases, hypertension, tumors No
24. M Caesarean section 6 13 25 Mild Asperger disorder   Cardiovascular diseases, hypertension, tumors Oat grass: lactose intolerant (patient), grass allergy (mother, uncle)
25. M Caesarean section 12 months 18 months 39 Severe Pervasive disorder NOS Dysgenetic pathology ndd; epileptic syndrome pharmacological treatment   No
26. M Natural Not reported 18 46 Severe Autistic disorder Epileptic syndrome pharmacological treatment   Psoriasis (father), lactose intolerance (mother)
27. M Caesarean section 6 20 51 Severe Pervasive disorder NOS Probable dysgenetic pathology ndd; reduced cognitive skills, ongoing antiepileptic treatment Cardiovascular diseases, hypertension, dyslipidemia No
28. F Natural 6 13 31 Mild Autistic disorder   Cardiovascular diseases, hypertension, tumors Grass, mite allergies (father)
29. M Natural 15 months 20 months 49 Severe Autistic disorder Genetic pathology ndd; moderate-to-severe cognitive disorder Cardiovascular diseases, hypertension, neuropsychiatric diseases Nickel allergy (grandmother), psoriasis (mother)
  1. NOS not otherwise specified
  2. ndd not defined diagnosis