Fig. 3
From: Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia
Effect of PI3K or mTOR inhibitors on the protein levels of mPGES-1 and COX-2 at 24 and 48 h after stimulation with poly(I:C) in microglia. a, b Effect of LY294002, rapamycin, or NVP-BEZ235 (PI3K, mTOR, or PI3K/mTOR dual inhibitors, respectively) on the protein levels of mPGES-1, COX-2, and actin at 24 h (a) or 48 h (b) after poly(I:C) stimulation. c Immunoblot analysis of protein levels of COX-2, mPGES-1, and actin in poly(I:C)-activated microglia 48 h after stimulation. *P < 0.05, **P < 0.01, and ***P < 0.001 in comparison with the respective poly(I:C) control