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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Myeloid dendritic cells are decreased in peripheral blood of Alzheimer’s disease patients in association with disease progression and severity of depressive symptoms

Fig. 1

Representative dot plots showing the gating strategy to identify mDCs and pDCs by flow cytometry. Whole peripheral leukocytes were selected from live cells based on forward scatter and side scatter characteristics (a, gate R1). Blood DCs were then selected within R1 positive cells as negative for lineage markers (lin-1) (b, gate R2). Finally, blood DCs were identified as mDC (d, HLA-DR+/CD11c+/CD123−, gate R3) or pDC (f, HLA-DR+/CD11c−/CD123+, gate R4) in comparison to respective isotype control monoclonal antibodies (c, e)

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Journal of Neuroinflammation

ISSN: 1742-2094