| |
HC
|
MCI
|
AD
|
AD w/o AChEI
|
AD AChEI
|
|---|
|
n
|
73
|
65
|
106
|
40
|
66
|
|
Gender (female, %)
|
57.2
|
57.0
|
51.9
|
55.0
|
50.0
|
|
Age (years)
|
71.5 ± 0.5
|
71.2 ± 0.7
|
72.1 ± 0.6
|
72.3 ± 1.0
|
71.9 ± 0.8
|
|
Education (years)
|
11.3 ± 0.5
|
9.0 ± 0.5*
|
8.5 ± 0.5**
|
9.0 ± 0.7*
|
8.1 ± 0.7**
|
|
MMSE
|
28.6 ± 0.1
|
27.0 ± 0.2**
|
20.9 ± 0.4**
|
22.0 ± 0.6**
|
20.0 ± 0.6**
|
|
ADL
|
5.9 ± 0.3
|
6.1 ± 0.05
|
8.5 ± 0.3**
|
8.0 ± 0.3**
|
8.9 ± 0.5**
|
|
IADL
|
6.7 ± 0.2
|
7.2 ± 0.2
|
13.8 ± 0.6**
|
12.9 ± 0.8**
|
14.6 ± 0.8**
|
|
NPI dep. (F × S)
|
1.3 ± 0.2
|
2.1 ± 0.2*
|
3.0 ± 0.2**
|
3.4 ± 0.4**
|
2.7 ± 0.3**
|
- Data are expressed as mean ± SEM; *p < 0.005 and **p < 0.0005 vs HC
-
MMSE mini-mental status examination, ADL activities of daily living, IADL instrumental activities of daily living, NPI dep. (F × S) neuropsychiatric inventory–depression (frequency × severity)
