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Table 1 Demographic and clinical characteristics of HC, MCI, and AD subjects

From: Myeloid dendritic cells are decreased in peripheral blood of Alzheimer’s disease patients in association with disease progression and severity of depressive symptoms

  HC MCI AD AD w/o AChEI AD AChEI
n 73 65 106 40 66
Gender (female, %) 57.2 57.0 51.9 55.0 50.0
Age (years) 71.5 ± 0.5 71.2 ± 0.7 72.1 ± 0.6 72.3 ± 1.0 71.9 ± 0.8
Education (years) 11.3 ± 0.5 9.0 ± 0.5* 8.5 ± 0.5** 9.0 ± 0.7* 8.1 ± 0.7**
MMSE 28.6 ± 0.1 27.0 ± 0.2** 20.9 ± 0.4** 22.0 ± 0.6** 20.0 ± 0.6**
ADL 5.9 ± 0.3 6.1 ± 0.05 8.5 ± 0.3** 8.0 ± 0.3** 8.9 ± 0.5**
IADL 6.7 ± 0.2 7.2 ± 0.2 13.8 ± 0.6** 12.9 ± 0.8** 14.6 ± 0.8**
NPI dep. (F × S) 1.3 ± 0.2 2.1 ± 0.2* 3.0 ± 0.2** 3.4 ± 0.4** 2.7 ± 0.3**
  1. Data are expressed as mean ± SEM; *p < 0.005 and **p < 0.0005 vs HC
  2. MMSE mini-mental status examination, ADL activities of daily living, IADL instrumental activities of daily living, NPI dep. (F × S) neuropsychiatric inventory–depression (frequency × severity)