Table 2 IC₅₀ (μM) based on MTT (A-1 and B-1) and LDHR data (A-2 and B-2) of NaSH and STS at different pre-incubation times in THP-1 cells and U373 cells

Pre-incubation time

NaSH

STS

NaSH

STS

2 h

28.55 ± 2.32

121.53 ± 3.25

28.55 ± 3.32

95.53 ± 3.25

4 h

23.83 ± 2.34

96.47 ± 2.44

22.43 ± 3.34

49.63 ± 2.44

8 h

10.35 ± 2.11

53.55 ± 2.46

9.44 ± 2.11

30.27 ± 2.46

12 h

5.83 ± 1.47

35.73 ± 1.78

4.47 ± 1.83

19.57 ± 1.78

Pre-incubation time

NaSH

STS

NaSH

STS

2 h

15.33 ± 0.88

173.53 ± 18.75

32.48 ± 2.32

98.38 ± 7.25

4 h

3.83 ± 0.56

100.47 ± 12.44

25.18 ± 2.21

71.05 ± 4.44

8 h

2.11 ± 0.16

61.81 ± 5.46

10.17 ± 1.11

47.91 ± 3.46

12 h

1.42 ± 0.22

33.51 ± 2.31

1.84 ± 0.28

32.22 ± 2.78