Fig. 4From: RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitisRGS10-null lymphocytes displayed attenuated recall response to MOG35â55. WT and RGS10-null mice were immunized with MOG35â55 as described in the âMethodsâ section. Ten days later, (a) lymph node cells or (b) splenocytes were isolated and re-stimulated ex vivo with the indicated concentrations of MOG35â55 peptide for 72Â h. Proliferation was assessed via MTS incorporation assay. c After 72Â h, cytokine secretion by WT and RGS10-null MOG35â55-re-stimulated lymph node cells was determined by MSD assay. **pâ<â0.01, ***pâ<â0.001, two-way ANOVA with Bonferroni post hoc test (nâ=â3â4 mice per group)Back to article page