Fig. 5

Expression of chemokines (a, c) and cytokines (b, d) in whole retinas following injection of NR58-3.14.3 and light damage. a, b All genes assessed exhibited significant up-regulation at 0 day post-LD in both treatment groups. However, Ccl3, Ccl4, and Il6 had significantly lower expression (P < 0.05) in retinas injected with NR58-3.14.3 compared to PBS controls. c, d By 7 days post-LD, up-regulation of all genes assessed was only 10–20 % of that observed at 0 day, with no difference between NR58-3.14.3- and PBS-injected groups (P > 0.05). 0 day N = 11–12 per group, 7 days N = 5 per group