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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Potential role of microRNA-7 in the anti-neuroinflammation effects of nicorandil in astrocytes induced by oxygen-glucose deprivation

Fig. 2

Nicorandil restrains OGD-induced upregulation of Herpud2 mRNA via miR-7. Time-course of OGD induced the changes of miR-7 (a) and Herpud2 mRNA (b) in astrocytes. c The target of miR-7 to Herpud2 3′UTR via Dual Luciferase Reporter Assays. Expression of miR-7 (d) and Herpud2 mRNA (e) pretreated by nicorandil. Data are represented as means ± S.E.M. from four independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001 vs. control; # P < 0.05, ### P < 0.001 vs. OGD group

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