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Table 1 Summary characteristics of participating studies

From: Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD)

 

Number of individuals

Mean age (years) (SD)

Females

Study

Cases

GA cases

NV cases

GA and NV cases

Controls

Total

Cases

Controls

Cases (%)

Controls (%)

AUS study

633

137

496

0

404

1037

75.95 (8.50)

71.03 (6.92)

64.60

55.40

WUE study

547

220

287

40

384

931

73.54 (6.74)

78.26 (5.30)

63.90

63.02

MUE/TUE study

356

97

129

130

321

677

76.16 (7.54)

69.50 (8.25)

64.89

55.80

Full study

1536

454

912

170

1109

2645

75.14 (7.78)

73.09 (7.83)

64.45

58.15

  1. GA geographic atrophy, NV neovascular disease, SD standard deviation, AUS Australian study, WUE/MUE/TUE German study