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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK

Fig. 2

Resveratrol inhibits phosphorylation of c-Fos and CGRP in the STN. Immunofluorescence analysis data show CGRP expression and c-Fos-immunoreactive neuron number. The CGRP and c-Fos level was significantly increased by CCI, and resveratrol suppressed the increase of CGRP expression (a) and attenuated the increase of c-Fos-immunoreactive neuron number (b). Resveratrol alone had no effect on CGRP expression and c-Fos-immunoreactive neuron number. n = 5, five images per animal. *P < 0.05 and **P < 0.01 versus control; and # P < 0.05 and ## P < 0.01 versus the CCI group

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