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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK

Fig. 4

Resveratrol inhibits the activation of microglia and astrocytes in rat STN. a, b Immunofluorescence analysis data show GFAP and IBA-1 expression (n = 5, five images per animal). CCI increased GFAP and IBA-1 immunoreactivity in the STN, whereas resveratrol (400 mg/kg, p.o.) downregulated the expression of both markers. *P < 0.05 and **P < 0.01 versus control; and # P < 0.05 and ## P < 0.01 versus the CCI group

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